KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
18.79
Human Site:
Y232
Identified Species:
34.44
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
Y232
R
L
K
K
R
K
G
Y
Q
G
A
M
V
E
K
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
E228
R
I
K
K
R
K
G
E
A
M
A
L
N
E
K
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
L41
K
Y
L
A
K
L
K
L
P
P
L
S
K
C
E
Dog
Lupus familis
XP_542675
460
51324
Y173
M
N
G
G
D
I
R
Y
H
I
Y
N
V
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
Y232
R
L
K
K
K
K
G
Y
Q
G
A
I
V
E
K
Rat
Rattus norvegicus
Q63651
564
63750
Y232
R
L
K
K
R
K
G
Y
Q
G
A
I
V
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
Y232
R
L
K
K
R
K
G
Y
Q
G
A
M
V
E
K
Chicken
Gallus gallus
NP_990026
593
64642
Y262
R
L
K
K
R
Q
G
Y
E
A
A
M
V
E
K
Frog
Xenopus laevis
NP_001087513
575
66421
E228
R
I
K
K
R
K
G
E
S
M
A
L
N
E
K
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
M146
K
K
E
E
K
H
I
M
S
E
R
N
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
E351
R
I
K
K
R
K
G
E
S
M
V
L
I
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
E245
R
V
K
K
R
H
A
E
T
L
S
L
N
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
I454
V
I
V
K
K
N
E
I
A
H
T
I
G
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
60
0
13.3
N.A.
86.6
93.3
N.A.
100
80
60
6.6
N.A.
53.3
N.A.
40
N.A.
P-Site Similarity:
100
73.3
20
20
N.A.
100
100
N.A.
100
93.3
73.3
33.3
N.A.
73.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
16
8
54
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
31
8
8
0
0
0
77
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
62
0
0
31
0
0
8
0
0
% G
% His:
0
0
0
0
0
16
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
31
0
0
0
8
8
8
0
8
0
24
8
0
0
% I
% Lys:
16
8
70
77
31
54
8
0
0
0
0
0
8
0
70
% K
% Leu:
0
39
8
0
0
8
0
8
0
8
8
31
0
8
8
% L
% Met:
8
0
0
0
0
0
0
8
0
24
0
24
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
16
24
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
31
0
0
0
0
0
0
% Q
% Arg:
70
0
0
0
62
0
8
0
0
0
8
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
24
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% T
% Val:
8
8
8
0
0
0
0
0
0
0
8
0
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
47
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _